2006 Experimental Biology Meeting
A socializer for regular and emeritus members is
scheduled for the AACBNC at EB 2006 in San
Francisco on Saturday, April 1.  The socializer will be
held from
5:30-7:00 pm at the Argent Hotel in the Franciscan I
room and is sponsored by The Anatomical Record, a
Wiley-Liss publication.  Members are encouraged to
bring their spouse or a guest.

The dates of EB 2006 are Saturday, April 1 -
Wednesday, April 5, 2006.   Further details
regarding the meeting can be found at

for the American Association of Anatomists at EB 2006
Supported by JEOL USA, Inc. through the AACBNC

Harvard Medical School

Sunday, April 2; 5:15 - 6:15 pm
in Room 103 Moscone Convention Center

"The Platelet Angiogenesis Proteome for Early
Detection of Cancer"
New Functions of Spectrin & the
Membrane Skeleton

Tuesday, April 4, 10:30 AM - 12:30 PM, Room 123

Co-sponsored by the Association of Anatomy, Cell Biology
and Neurobiology Chairpersons

Chair: Steven Goodman
(Univ. of Texas, Dallas)

Warren Zimmer
(Texas A&M Health Science Center)
Spectrin's Key Role in Synaptic Transmission

Muriel Lambert
(UMDNJ-New Jersey Medical School)
Spectrin: Its Role in DNA Repair

Troy Stevens
(Univ. of South Alabama College of Medicine)
Control of Store Operated Calcium Entry by the
Spectrin Membrane Skeleton

Steven Goodman
(Univ. of Texas , Dallas)
Spectrin is a Chimeric E2/E3 Ubiquitin Ligase
Experimental Biology 2006
Spectrin was first isolated from RBCs in the 1960s and
its role as a major structural component of the RBC
membrane skeleton was well defined by 1980. In 1981,
demonstrated that spectrin was a ubiquitous protein
in nonerythroid cells. Twenty-five years later, the
speakers will discuss spectrin’s role in
neurotransmission, DNA repair, the role of a spectrin
binding partner in Ca release from internal stores, and
recent studies demonstrating that spectrin has a
previously unknown function as a chimeric E2/E3
ubiquitin conjugating/ligating enzyme.